Trifexis side effects in dogs

88 reports sent to the FDA between 2012 and 2026 involve Trifexis in dogs. The most reported problems were seizures, diarrhea, vomiting. 85% were marked serious.

88Reports
85%Marked serious
0.0%Only medicine involved
8.0%Recovered
5.7%Died or euthanised
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About this medicine

Type: medicine.

Most reported side effects

Seizures
9 10%
Diarrhea
4 4.5%
Vomiting
4 4.5%
Kidney problems
3 3.4%
Drug dose administration interval too long
3 3.4%
Lethargy
3 3.4%
Wobbliness (ataxia)
3 3.4%
Blood problems
3 3.4%
Medication error
3 3.4%
Liver problems
2 2.3%
Breathing problems
2 2.3%
Behaviour change
2 2.3%
Bruising
2 2.3%
Eye or vision problems
2 2.3%
Growling
2 2.3%

Share = percentage of this medicine's reports that mention the problem. One report can list several problems.

Reports that it didn't work

Some reports are about the medicine not working (for example a dog still getting fleas or heartworm), not about a side effect.

Didn't work as expected
5 5.7%
Didn't stop fleas
2 2.3%
Didn't stop worms
1 1.1%

How soon problems started

Same day
4 12%
1–2 days
1 3.0%
3–7 days
0 0.0%
1–4 weeks
1 3.0%
Over a month
27 82%

Time from the first dose to the first sign, where both dates were reported (33 reports).

How the animals did

Recovered
5 5.7%
Recovered with lasting effects
2 2.3%
Still unwell when reported
69 78%
Died
3 3.4%
Euthanised
2 2.3%
Not known
7 8.0%

Breeds named most often

Popular breeds appear more often because there are more of them.

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