Anxiety after Trazodone in dogs

101 reports to the FDA describe anxiety in dogs given Trazodone. That is 4.0% of all reports for this medicine, compared with 0.5% across reports for all dog medicines, so it is reported unusually often with this medicine.

101Reports
45%Marked serious
17%Recovered
11%Died or euthanised
42 daysTypical onset
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How soon it started

Same day
17 23%
1–2 days
10 13%
3–7 days
4 5.3%
1–4 weeks
3 4.0%
Over a month
41 55%

How the animals did

Recovered
16 16%
Recovered with lasting effects
1 1.0%
Still unwell when reported
36 36%
Died
1 1.0%
Euthanised
10 9.9%
Not known
37 37%

Problems reported at the same time

Age of the animals

Under 1 year
2
1–3 years
19
4–7 years
27
8–11 years
30
12+ years
22

About this medicine

Trazodone reduces anxiety and stress.

Questions owners ask

Can Trazodone cause anxiety in dogs?
101 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 42 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Anxiety with similar medicines

All reported side effects of Trazodone in dogs · Medicines most reported with anxiety