Loss of appetite after Tiletamine + Zolazepam in dogs

The FDA has received 60 reports of loss of appetite in dogs after Tiletamine + Zolazepam. That is 4.1% of all reports for this medicine, compared with 8.4% across reports for all dog medicines, so it is reported less often than average with this medicine.

60Reports
45%Marked serious
17%Recovered
37%Died or euthanised
3 daysTypical onset
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How soon it started

Same day
9 21%
1–2 days
10 24%
3–7 days
9 21%
1–4 weeks
10 24%
Over a month
4 9.5%

How the animals did

Recovered
9 15%
Recovered with lasting effects
1 1.7%
Still unwell when reported
16 27%
Died
13 22%
Euthanised
9 15%
Not known
12 20%

Problems reported at the same time

34 57%
33 55%
22 37%
18 30%
Weight loss
13 22%

Age of the animals

Under 1 year
6
1–3 years
15
4–7 years
21
8–11 years
13
12+ years
4

About this medicine

Type: medicine.

Questions owners ask

Can Tiletamine + Zolazepam cause loss of appetite in dogs?
60 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 3 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Loss of appetite with similar medicines

All reported side effects of Tiletamine + Zolazepam in dogs · Medicines most reported with loss of appetite