Behaviour change after Tiletamine + Zolazepam in dogs

39 reports to the FDA describe behaviour change in dogs given Tiletamine + Zolazepam. That is 2.7% of all reports for this medicine, compared with 2.5% across reports for all dog medicines.

39Reports
49%Marked serious
23%Recovered
21%Died or euthanised
Same dayTypical onset
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How soon it started

Same day
16 62%
1–2 days
3 12%
3–7 days
2 7.7%
1–4 weeks
1 3.8%
Over a month
4 15%

How the animals did

Recovered
9 23%
Still unwell when reported
11 28%
Died
4 10%
Euthanised
4 10%
Not known
11 28%

Problems reported at the same time

Age of the animals

Under 1 year
7
1–3 years
11
4–7 years
8
8–11 years
5
12+ years
3

About this medicine

Type: medicine.

Questions owners ask

Can Tiletamine + Zolazepam cause behaviour change in dogs?
39 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within the same day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Behaviour change with similar medicines

All reported side effects of Tiletamine + Zolazepam in dogs · Medicines most reported with behaviour change