Lateral recumbency after Tigilanol Tiglate in dogs

The FDA has received 20 reports of lateral recumbency in dogs after Tigilanol Tiglate. That is 1.0% of all reports for this medicine, compared with 0.3% across reports for all dog medicines, so it is reported unusually often with this medicine.

20Reports

100%Marked serious

15%Recovered

65%Died or euthanised

Same dayTypical onset

How soon it started

Same day

11 55%

1–2 days

7 35%

3–7 days

1 5.0%

1–4 weeks

1 5.0%

Over a month

0 0.0%

How the animals did

Recovered

3 15%

Died

5 25%

Euthanised

8 40%

Not known

4 20%

Problems reported at the same time

Loss of appetite

19 95%

Injection site reaction

17 85%

15 75%

13 65%

12 60%

12 60%

9 45%

9 45%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: medicine.

Questions owners ask

Can Tigilanol Tiglate cause lateral recumbency in dogs?: 20 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within the same day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Lateral recumbency with similar medicines

Lateral recumbency after Melarsomine (Immiticide) 159 reports · 0.7% of its reports
Lateral recumbency after Polysulfated Glycosaminoglycan 30 reports · 0.5% of its reports
Lateral recumbency after Diphenhydramine 94 reports · 2.0% of its reports
Lateral recumbency after Butorphanol 56 reports · 1.3% of its reports
Lateral recumbency after Cefpodoxime 33 reports · 0.8% of its reports
Lateral recumbency after Tramadol 58 reports · 1.5% of its reports
Lateral recumbency after Propofol 31 reports · 1.0% of its reports
Lateral recumbency after Isoflurane 34 reports · 1.2% of its reports
Lateral recumbency after Cephalexin 21 reports · 0.8% of its reports
Lateral recumbency after Famotidine 71 reports · 2.7% of its reports

All reported side effects of Tigilanol Tiglate in dogs · Medicines most reported with lateral recumbency