Lateral recumbency after Melarsomine (Immiticide) in dogs

159 reports to the FDA describe lateral recumbency in dogs given Melarsomine. That is 0.7% of all reports for this medicine, compared with 0.3% across reports for all dog medicines, so it is reported unusually often with this medicine.

159Reports
90%Marked serious
23%Recovered
21%Died or euthanised
5 daysTypical onset
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How soon it started

Same day
63 42%
1–2 days
7 4.6%
3–7 days
16 11%
1–4 weeks
30 20%
Over a month
35 23%

How the animals did

Recovered
36 23%
Recovered with lasting effects
1 0.6%
Still unwell when reported
58 36%
Died
20 13%
Euthanised
14 8.8%
Not known
30 19%

Problems reported at the same time

Age of the animals

Under 1 year
1
1–3 years
91
4–7 years
53
8–11 years
11
12+ years
3

About this medicine

Melarsomine treats adult heartworm infection (a series of injections given by a vet).

Products with this ingredient include Immiticide, Diroban. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Melarsomine cause lateral recumbency in dogs?
159 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 5 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Lateral recumbency with similar medicines

All reported side effects of Melarsomine in dogs · Medicines most reported with lateral recumbency