Unable to stand after Spinosad (Comfortis) in dogs

111 reports to the FDA describe unable to stand in dogs given Spinosad. That is 0.2% of all reports for this medicine, compared with 0.3% across reports for all dog medicines, so it is reported less often than average with this medicine.

111Reports
63%Marked serious
50%Recovered
21%Died or euthanised
7 daysTypical onset
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How soon it started

Same day
26 33%
1–2 days
12 15%
3–7 days
3 3.8%
1–4 weeks
9 11%
Over a month
30 38%

How the animals did

Recovered
38 34%
Recovered with lasting effects
17 15%
Still unwell when reported
8 7.2%
Died
9 8.1%
Euthanised
14 13%
Not known
25 23%

Problems reported at the same time

Age of the animals

Under 1 year
8
1–3 years
21
4–7 years
36
8–11 years
27
12+ years
16

About this medicine

Spinosad kills fleas; monthly chewable.

Products with this ingredient include Comfortis. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Spinosad cause unable to stand in dogs?
111 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 7 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Unable to stand with similar medicines

All reported side effects of Spinosad in dogs · Medicines most reported with unable to stand