Reluctant to move after Spinosad (Comfortis) in dogs

189 reports to the FDA describe reluctant to move in dogs given Spinosad. That is 0.3% of all reports for this medicine, compared with 0.5% across reports for all dog medicines.

189Reports

24%Marked serious

32%Recovered

14%Died or euthanised

1 daysTypical onset

How soon it started

Same day

36 47%

1–2 days

10 13%

3–7 days

3 3.9%

1–4 weeks

7 9.2%

Over a month

20 26%

How the animals did

Recovered

43 23%

Recovered with lasting effects

17 9.0%

Still unwell when reported

10 5.3%

Died

21 11%

Euthanised

6 3.2%

Not known

92 49%

Problems reported at the same time

96 51%

71 38%

53 28%

49 26%

33 17%

31 16%

30 16%

27 14%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Spinosad kills fleas; monthly chewable.

Products with this ingredient include Comfortis. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Spinosad cause reluctant to move in dogs?: 189 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 1 day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Reluctant to move with similar medicines

Reluctant to move after Lufenuron + Milbemycin Oxime (Sentinel) 68 reports · 0.3% of its reports
Reluctant to move after Imidacloprid + Moxidectin (Advantage Multi) 57 reports · 0.4% of its reports
Reluctant to move after Nitenpyram (Capstar) 43 reports · 0.4% of its reports
Reluctant to move after Lufenuron + Milbemycin Oxime + Praziquantel (Sentinel Spectrum) 27 reports · 0.3% of its reports

All reported side effects of Spinosad in dogs · Medicines most reported with reluctant to move