Eye or vision problems after Spinosad (Comfortis) in dogs

497 reports to the FDA describe eye or vision problems in dogs given Spinosad. That is 0.9% of all reports for this medicine, compared with 0.7% across reports for all dog medicines.

497Reports
41%Marked serious
31%Recovered
10%Died or euthanised
24 daysTypical onset
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How soon it started

Same day
48 26%
1–2 days
18 9.7%
3–7 days
14 7.5%
1–4 weeks
23 12%
Over a month
83 45%

How the animals did

Recovered
95 19%
Recovered with lasting effects
59 12%
Still unwell when reported
19 3.8%
Died
29 5.8%
Euthanised
22 4.4%
Not known
273 55%

Problems reported at the same time

Age of the animals

Under 1 year
64
1–3 years
146
4–7 years
109
8–11 years
108
12+ years
46

About this medicine

Spinosad kills fleas; monthly chewable.

Products with this ingredient include Comfortis. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Spinosad cause eye or vision problems in dogs?
497 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 24 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Eye or vision problems with similar medicines

All reported side effects of Spinosad in dogs · Medicines most reported with eye or vision problems