Excessive licking and/or grooming after Spinosad (Comfortis) in dogs

The FDA has received 70 reports of excessive licking and/or grooming in dogs after Spinosad. That is 0.1% of all reports for this medicine, compared with 0.1% across reports for all dog medicines.

70Reports
4.3%Marked serious
16%Recovered
2.9%Died or euthanised
31 daysTypical onset
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How soon it started

Same day
1 10%
1–2 days
2 20%
3–7 days
0 0.0%
1–4 weeks
1 10%
Over a month
6 60%

How the animals did

Recovered
5 7.1%
Recovered with lasting effects
6 8.6%
Still unwell when reported
4 5.7%
Died
2 2.9%
Not known
53 76%

Problems reported at the same time

Age of the animals

Under 1 year
5
1–3 years
22
4–7 years
23
8–11 years
15
12+ years
4

About this medicine

Spinosad kills fleas; monthly chewable.

Products with this ingredient include Comfortis. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Spinosad cause excessive licking and/or grooming in dogs?
70 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 31 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Excessive licking and/or grooming with similar medicines

All reported side effects of Spinosad in dogs · Medicines most reported with excessive licking and/or grooming