Didn't stop mites after Selamectin (Revolution) in dogs

735 reports to the FDA describe didn't stop mites in dogs given Selamectin. That is 2.5% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

735Reports
2.4%Marked serious
0.4%Recovered
0.3%Died or euthanised
42 daysTypical onset
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How soon it started

Same day
11 8.3%
1–2 days
2 1.5%
3–7 days
8 6.0%
1–4 weeks
39 29%
Over a month
73 55%

How the animals did

Recovered
3 0.4%
Still unwell when reported
77 10%
Died
2 0.3%
Not known
653 89%

Problems reported at the same time

Age of the animals

Under 1 year
316
1–3 years
147
4–7 years
81
8–11 years
50
12+ years
13

About this medicine

Selamectin prevents heartworm and treats fleas, ear mites and some worms (spot-on).

Products with this ingredient include Revolution. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Some herding breeds (for example Collies) carry the MDR1 gene variant and can be more sensitive to this drug class at high doses.

Questions owners ask

Can Selamectin cause didn't stop mites in dogs?
735 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 42 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

All reported side effects of Selamectin in dogs · Medicines most reported with didn't stop mites