Elevated globulins after Sarolaner (Simparica) in dogs
The FDA has received 34 reports of elevated globulins in dogs after Sarolaner. That is 0.2% of all reports for this medicine, compared with 0.2% across reports for all dog medicines.
34Reports
79%Marked serious
8.8%Recovered
29%Died or euthanised
4 daysTypical onset
Sponsored
How soon it started
How the animals did
Problems reported at the same time
Age of the animals
About this medicine
Sarolaner kills fleas, ticks and some mites; monthly.
Products with this ingredient include Simparica. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.
In 2018 the FDA alerted owners and vets that isoxazoline products have been associated with neurologic reactions such as muscle tremors, wobbliness (ataxia) and seizures, including in animals with no history of them.
Questions owners ask
- Can Sarolaner cause elevated globulins in dogs?
- 34 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
- How soon after a dose was it reported?
- In half of the reports with dates, it started within 4 days of the first dose.
- What should I do?
- Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).
Elevated globulins with similar medicines
- Elevated globulins after Fluralaner (Bravecto) 207 reports · 0.3% of its reports
- Elevated globulins after Afoxolaner (NexGard) 119 reports · 0.2% of its reports
- Elevated globulins after Lotilaner (Credelio) 37 reports · 0.4% of its reports
- Elevated globulins after Afoxolaner + Moxidectin + Pyrantel (NexGard PLUS) 31 reports · 0.3% of its reports
All reported side effects of Sarolaner in dogs · Medicines most reported with elevated globulins