Sam-e side effects in dogs

52 reports sent to the FDA between 2015 and 2026 involve Sam-e in dogs. The most reported problems were loss of appetite, liver problems, lethargy. 60% were marked serious.

52Reports
60%Marked serious
0.0%Only medicine involved
12%Recovered
7.7%Died or euthanised
SponsoredWorried about your pet? Ask a veterinarian online, 24/7

About this medicine

Type: medicine.

Most reported side effects

Liver problems
18 35%
Lethargy
13 25%
Diarrhea
8 15%
Underdose
8 15%
Vomiting
7 13%
Hyperkalaemia
6 12%
Breathing problems
5 9.6%
Blood problems
5 9.6%
Itching
5 9.6%
Kidney problems
5 9.6%
Abnormal ultrasound finding
5 9.6%
Low sodium-potassium ratio (na:k ratio)
4 7.7%
Haemolysis
4 7.7%
Weight loss
4 7.7%

Share = percentage of this medicine's reports that mention the problem. One report can list several problems.

Reports that it didn't work

Some reports are about the medicine not working (for example a dog still getting fleas or heartworm), not about a side effect.

Didn't work as expected
7 13%

How soon problems started

Same day
1 2.3%
1–2 days
2 4.7%
3–7 days
2 4.7%
1–4 weeks
6 14%
Over a month
32 74%

Time from the first dose to the first sign, where both dates were reported (43 reports).

How the animals did

Recovered
6 12%
Still unwell when reported
11 21%
Euthanised
4 7.7%
Not known
31 60%

Breeds named most often

Popular breeds appear more often because there are more of them.

Other medicines for dogs