Weakness after Pyrantel in dogs

The FDA has received 118 reports of weakness in dogs after Pyrantel. That is 2.5% of all reports for this medicine, compared with 1.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

118Reports

50%Marked serious

12%Recovered

39%Died or euthanised

1 daysTypical onset

How soon it started

Same day

26 41%

1–2 days

14 22%

3–7 days

8 13%

1–4 weeks

9 14%

Over a month

7 11%

How the animals did

Recovered

13 11%

Recovered with lasting effects

1 0.8%

Still unwell when reported

21 18%

Died

32 27%

Euthanised

14 12%

Not known

37 31%

Problems reported at the same time

46 39%

46 39%

42 36%

37 31%

30 25%

20 17%

20 17%

16 14%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Pyrantel treats roundworms and hookworms.

Questions owners ask

Can Pyrantel cause weakness in dogs?: 118 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 1 day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Weakness with similar medicines

Weakness after Pyrantel + Sarolaner (Simparica Trio) 352 reports · 0.7% of its reports
Weakness after Febantel + Praziquantel + Pyrantel (Drontal Plus) 50 reports · 0.7% of its reports
Weakness after Fenbendazole 146 reports · 2.5% of its reports
Weakness after Praziquantel + Pyrantel 79 reports · 2.1% of its reports

All reported side effects of Pyrantel in dogs · Medicines most reported with weakness