Immediate pain upon injection after Prednisone in dogs

137 reports to the FDA describe immediate pain upon injection in dogs given Prednisone. That is 1.5% of all reports for this medicine, compared with 0.0% across reports for all dog medicines, so it is reported unusually often with this medicine.

137Reports

14%Marked serious

81%Recovered

2.2%Died or euthanised

73 daysTypical onset

How soon it started

Same day

22 34%

1–2 days

1 1.5%

3–7 days

0 0.0%

1–4 weeks

3 4.6%

Over a month

39 60%

How the animals did

Recovered

111 81%

Still unwell when reported

10 7.3%

Died

1 0.7%

Euthanised

2 1.5%

Not known

13 9.5%

Problems reported at the same time

Vocalising

51 37%

Behaviour change

12 8.8%

Medication error

8 5.8%

Injection site reaction

6 4.4%

6 4.4%

6 4.4%

5 3.6%

5 3.6%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Prednisone reduces inflammation and immune activity.

Steroids commonly cause increased thirst, urination and appetite, especially at higher doses.

Questions owners ask

Can Prednisone cause immediate pain upon injection in dogs?: 137 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 73 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

All reported side effects of Prednisone in dogs · Medicines most reported with immediate pain upon injection