Decreased urine concentration after Prednisone in dogs

103 reports to the FDA describe decreased urine concentration in dogs given Prednisone. That is 1.2% of all reports for this medicine, compared with 0.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

103Reports

69%Marked serious

5.8%Recovered

17%Died or euthanised

25 daysTypical onset

How soon it started

Same day

8 14%

1–2 days

3 5.2%

3–7 days

6 10%

1–4 weeks

16 28%

Over a month

25 43%

How the animals did

Recovered

6 5.8%

Still unwell when reported

40 39%

Died

5 4.9%

Euthanised

13 13%

Not known

39 38%

Problems reported at the same time

49 48%

45 44%

44 43%

40 39%

32 31%

27 26%

23 22%

23 22%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Prednisone reduces inflammation and immune activity.

Steroids commonly cause increased thirst, urination and appetite, especially at higher doses.

Questions owners ask

Can Prednisone cause decreased urine concentration in dogs?: 103 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 25 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Decreased urine concentration with similar medicines

Decreased urine concentration after Prednisolone + Trimeprazine 28 reports · 1.3% of its reports

All reported side effects of Prednisone in dogs · Medicines most reported with decreased urine concentration