Application site reaction after Prednisone in dogs

The FDA has received 59 reports of application site reaction in dogs after Prednisone. That is 0.7% of all reports for this medicine, compared with 0.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

59Reports
59%Marked serious
25%Recovered
8.5%Died or euthanised
4 daysTypical onset
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How soon it started

Same day
10 20%
1–2 days
13 26%
3–7 days
7 14%
1–4 weeks
10 20%
Over a month
10 20%

How the animals did

Recovered
15 25%
Still unwell when reported
8 14%
Died
3 5.1%
Euthanised
2 3.4%
Not known
31 53%

Problems reported at the same time

Age of the animals

Under 1 year
3
1–3 years
14
4–7 years
13
8–11 years
17
12+ years
12

About this medicine

Prednisone reduces inflammation and immune activity.

Steroids commonly cause increased thirst, urination and appetite, especially at higher doses.

Questions owners ask

Can Prednisone cause application site reaction in dogs?
59 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 4 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Application site reaction with similar medicines

All reported side effects of Prednisone in dogs · Medicines most reported with application site reaction