Skin scraping abnormal after Oclacitinib (Apoquel) in dogs

78 reports to the FDA describe skin scraping abnormal in dogs given Oclacitinib. That is 0.3% of all reports for this medicine, compared with 0.0% across reports for all dog medicines, so it is reported unusually often with this medicine.

78Reports

9.0%Marked serious

13%Recovered

3.8%Died or euthanised

84 daysTypical onset

How soon it started

Same day

1 1.6%

1–2 days

1 1.6%

3–7 days

1 1.6%

1–4 weeks

13 20%

Over a month

48 75%

How the animals did

Recovered

10 13%

Still unwell when reported

58 74%

Died

1 1.3%

Euthanised

2 2.6%

Not known

7 9.0%

Problems reported at the same time

Skin disorders

66 85%

Didn't work as expected

24 31%

Hair loss

22 28%

Pr-skin, lesion(s)

15 19%

Skin rash or irritation

13 17%

Skin and tissue infection

12 15%

Bacterial skin infection

9 12%

Itching

9 12%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Oclacitinib controls itching from allergies (tablet, a JAK inhibitor).

Products with this ingredient include Apoquel. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Oclacitinib cause skin scraping abnormal in dogs?: 78 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 84 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

All reported side effects of Oclacitinib in dogs · Medicines most reported with skin scraping abnormal