Head tilt - neurological disorder after Oclacitinib (Apoquel) in dogs

65 reports to the FDA describe head tilt - neurological disorder in dogs given Oclacitinib. That is 0.2% of all reports for this medicine, compared with 0.2% across reports for all dog medicines.

65Reports

66%Marked serious

11%Recovered

12%Died or euthanised

10 daysTypical onset

How soon it started

Same day

16 36%

1–2 days

2 4.4%

3–7 days

3 6.7%

1–4 weeks

7 16%

Over a month

17 38%

How the animals did

Recovered

7 11%

Still unwell when reported

37 57%

Died

3 4.6%

Euthanised

5 7.7%

Not known

13 20%

Problems reported at the same time

22 34%

20 31%

17 26%

14 22%

12 18%

11 17%

Circling - neurological disorder

9 14%

Seizures

8 12%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Oclacitinib controls itching from allergies (tablet, a JAK inhibitor).

Products with this ingredient include Apoquel. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Oclacitinib cause head tilt - neurological disorder in dogs?: 65 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 10 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Head tilt - neurological disorder with similar medicines

Head tilt - neurological disorder after Cyclosporine (Atopica) 24 reports · 0.2% of its reports

All reported side effects of Oclacitinib in dogs · Medicines most reported with head tilt - neurological disorder