Nexgard Plus side effects in dogs

50 reports sent to the FDA between 2024 and 2026 involve Nexgard Plus in dogs. The most reported problems were wobbliness (ataxia), seizures, inappropriate urination. 70% were marked serious.

50Reports
70%Marked serious
0.0%Only medicine involved
10%Recovered
2.0%Died or euthanised
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About this medicine

Type: medicine.

Most reported side effects

Wobbliness (ataxia)
5 10%
Seizures
4 8.0%
Inappropriate urination
4 8.0%
Tremors
4 8.0%
Vomiting
4 8.0%
Medication error
3 6.0%
Swelling
3 6.0%
Bone and joint disorder
3 6.0%
Abnormal radiograph finding
3 6.0%
Collapse
2 4.0%
Liver problems
2 4.0%
Urinary tract infection
2 4.0%
Proprioception deficit
2 4.0%
Lethargy
2 4.0%
Loss of appetite
2 4.0%

Share = percentage of this medicine's reports that mention the problem. One report can list several problems.

Reports that it didn't work

Some reports are about the medicine not working (for example a dog still getting fleas or heartworm), not about a side effect.

Didn't prevent heartworm
16 32%
Didn't work as expected
9 18%
Didn't stop worms
2 4.0%
Didn't stop fleas
1 2.0%

How soon problems started

Same day
2 6.1%
1–2 days
4 12%
3–7 days
2 6.1%
1–4 weeks
4 12%
Over a month
21 64%

Time from the first dose to the first sign, where both dates were reported (33 reports).

How the animals did

Recovered
5 10%
Still unwell when reported
44 88%
Euthanised
1 2.0%

Breeds named most often

Popular breeds appear more often because there are more of them.

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