Proteinuria after Metronidazole in dogs

72 reports to the FDA describe proteinuria in dogs given Metronidazole. That is 2.3% of all reports for this medicine, compared with 0.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

72Reports

81%Marked serious

15%Recovered

36%Died or euthanised

31 daysTypical onset

How soon it started

Same day

8 14%

1–2 days

4 7.0%

3–7 days

6 11%

1–4 weeks

10 18%

Over a month

29 51%

How the animals did

Recovered

10 14%

Recovered with lasting effects

1 1.4%

Still unwell when reported

26 36%

Died

3 4.2%

Euthanised

23 32%

Not known

9 13%

Problems reported at the same time

49 68%

46 64%

40 56%

37 51%

33 46%

30 42%

25 35%

24 33%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Metronidazole treats some bacterial and parasitic gut infections.

Questions owners ask

Can Metronidazole cause proteinuria in dogs?: 72 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 31 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Proteinuria with similar medicines

Proteinuria after Amoxicillin + Clavulanate (Clavamox) 138 reports · 2.6% of its reports
Proteinuria after Doxycycline 74 reports · 1.8% of its reports
Proteinuria after Cefovecin (Convenia) 50 reports · 1.3% of its reports
Proteinuria after Enrofloxacin (Baytril) 68 reports · 1.8% of its reports
Proteinuria after Amoxicillin 48 reports · 3.6% of its reports

All reported side effects of Metronidazole in dogs · Medicines most reported with proteinuria