Low platelet count after Metronidazole in dogs

The FDA has received 63 reports of low platelet count in dogs after Metronidazole. That is 2.0% of all reports for this medicine, compared with 0.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

63Reports
87%Marked serious
14%Recovered
44%Died or euthanised
9 daysTypical onset
SponsoredWorried about your pet? Ask a veterinarian online, 24/7

How soon it started

Same day
7 16%
1–2 days
6 14%
3–7 days
8 18%
1–4 weeks
12 27%
Over a month
11 25%

How the animals did

Recovered
8 13%
Recovered with lasting effects
1 1.6%
Still unwell when reported
22 35%
Died
6 9.5%
Euthanised
22 35%
Not known
4 6.3%

Problems reported at the same time

Age of the animals

Under 1 year
2
1–3 years
18
4–7 years
13
8–11 years
18
12+ years
12

About this medicine

Metronidazole treats some bacterial and parasitic gut infections.

Questions owners ask

Can Metronidazole cause low platelet count in dogs?
63 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 9 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Low platelet count with similar medicines

All reported side effects of Metronidazole in dogs · Medicines most reported with low platelet count