Hypoalbuminaemia after Metronidazole in dogs

157 reports to the FDA describe hypoalbuminaemia in dogs given Metronidazole. That is 5.1% of all reports for this medicine, compared with 0.6% across reports for all dog medicines, so it is reported unusually often with this medicine.

157Reports
79%Marked serious
12%Recovered
36%Died or euthanised
7 daysTypical onset
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How soon it started

Same day
23 18%
1–2 days
23 18%
3–7 days
21 17%
1–4 weeks
24 19%
Over a month
36 28%

How the animals did

Recovered
17 11%
Recovered with lasting effects
2 1.3%
Still unwell when reported
65 41%
Died
17 11%
Euthanised
39 25%
Not known
17 11%

Problems reported at the same time

Age of the animals

Under 1 year
19
1–3 years
26
4–7 years
43
8–11 years
42
12+ years
26

About this medicine

Metronidazole treats some bacterial and parasitic gut infections.

Questions owners ask

Can Metronidazole cause hypoalbuminaemia in dogs?
157 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 7 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Hypoalbuminaemia with similar medicines

All reported side effects of Metronidazole in dogs · Medicines most reported with hypoalbuminaemia