Respiratory distress after Melarsomine (Immiticide) in dogs

The FDA has received 140 reports of respiratory distress in dogs after Melarsomine. That is 0.6% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

140Reports
49%Marked serious
9.3%Recovered
46%Died or euthanised
4 daysTypical onset
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How soon it started

Same day
24 38%
1–2 days
6 9.4%
3–7 days
3 4.7%
1–4 weeks
17 27%
Over a month
14 22%

How the animals did

Recovered
13 9.3%
Still unwell when reported
20 14%
Died
58 41%
Euthanised
7 5.0%
Not known
42 30%

Problems reported at the same time

Age of the animals

Under 1 year
2
1–3 years
56
4–7 years
46
8–11 years
20
12+ years
7

About this medicine

Melarsomine treats adult heartworm infection (a series of injections given by a vet).

Products with this ingredient include Immiticide, Diroban. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Melarsomine cause respiratory distress in dogs?
140 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 4 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Respiratory distress with similar medicines

All reported side effects of Melarsomine in dogs · Medicines most reported with respiratory distress