Hyperkalaemia after Melarsomine (Immiticide) in dogs

23 reports to the FDA describe hyperkalaemia in dogs given Melarsomine. That is 0.1% of all reports for this medicine, compared with 0.3% across reports for all dog medicines, so it is reported less often than average with this medicine.

23Reports

65%Marked serious

8.7%Recovered

30%Died or euthanised

24 daysTypical onset

How soon it started

Same day

2 12%

1–2 days

0 0.0%

3–7 days

4 24%

1–4 weeks

5 29%

Over a month

6 35%

How the animals did

Recovered

2 8.7%

Still unwell when reported

5 22%

Died

5 22%

Euthanised

2 8.7%

Not known

9 39%

Problems reported at the same time

16 70%

14 61%

12 52%

11 48%

9 39%

9 39%

7 30%

6 26%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Melarsomine treats adult heartworm infection (a series of injections given by a vet).

Products with this ingredient include Immiticide, Diroban. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Melarsomine cause hyperkalaemia in dogs?: 23 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 24 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Hyperkalaemia with similar medicines

Hyperkalaemia after Polysulfated Glycosaminoglycan 25 reports · 0.5% of its reports
Hyperkalaemia after Diphenhydramine 26 reports · 0.6% of its reports
Hyperkalaemia after Cefpodoxime 26 reports · 0.6% of its reports
Hyperkalaemia after Tramadol 44 reports · 1.2% of its reports
Hyperkalaemia after Desoxycorticosterone Pivalate 117 reports · 3.5% of its reports
Hyperkalaemia after Famotidine 23 reports · 0.9% of its reports
Hyperkalaemia after Enalapril 70 reports · 4.2% of its reports
Hyperkalaemia after Furosemide 27 reports · 1.8% of its reports
Hyperkalaemia after Ursodiol 47 reports · 6.4% of its reports
Hyperkalaemia after Benazepril 28 reports · 4.4% of its reports

All reported side effects of Melarsomine in dogs · Medicines most reported with hyperkalaemia