Heart murmur after Melarsomine (Immiticide) in dogs

The FDA has received 63 reports of heart murmur in dogs after Melarsomine. That is 0.3% of all reports for this medicine, compared with 0.2% across reports for all dog medicines.

63Reports
57%Marked serious
9.5%Recovered
9.5%Died or euthanised
25 daysTypical onset
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How soon it started

Same day
6 11%
1–2 days
5 9.1%
3–7 days
5 9.1%
1–4 weeks
20 36%
Over a month
19 35%

How the animals did

Recovered
6 9.5%
Still unwell when reported
21 33%
Died
2 3.2%
Euthanised
4 6.3%
Not known
30 48%

Problems reported at the same time

Age of the animals

Under 1 year
0
1–3 years
24
4–7 years
30
8–11 years
8
12+ years
1

About this medicine

Melarsomine treats adult heartworm infection (a series of injections given by a vet).

Products with this ingredient include Immiticide, Diroban. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Melarsomine cause heart murmur in dogs?
63 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 25 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Heart murmur with similar medicines

All reported side effects of Melarsomine in dogs · Medicines most reported with heart murmur