Elevated amylase after Melarsomine (Immiticide) in dogs

87 reports to the FDA describe elevated amylase in dogs given Melarsomine. That is 0.4% of all reports for this medicine, compared with 0.3% across reports for all dog medicines.

87Reports

45%Marked serious

5.7%Recovered

21%Died or euthanised

13 daysTypical onset

How soon it started

Same day

4 8.9%

1–2 days

4 8.9%

3–7 days

7 16%

1–4 weeks

12 27%

Over a month

18 40%

How the animals did

Recovered

5 5.7%

Still unwell when reported

17 20%

Died

12 14%

Euthanised

6 6.9%

Not known

47 54%

Problems reported at the same time

60 69%

39 45%

39 45%

33 38%

31 36%

31 36%

26 30%

23 26%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Melarsomine treats adult heartworm infection (a series of injections given by a vet).

Products with this ingredient include Immiticide, Diroban. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Melarsomine cause elevated amylase in dogs?: 87 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 13 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Elevated amylase with similar medicines

Elevated amylase after Polysulfated Glycosaminoglycan 35 reports · 0.6% of its reports
Elevated amylase after Diphenhydramine 30 reports · 0.6% of its reports
Elevated amylase after Butorphanol 40 reports · 0.9% of its reports
Elevated amylase after Cefpodoxime 46 reports · 1.1% of its reports
Elevated amylase after Tramadol 36 reports · 1.0% of its reports
Elevated amylase after Desoxycorticosterone Pivalate 34 reports · 1.0% of its reports
Elevated amylase after Propofol 20 reports · 0.7% of its reports
Elevated amylase after Isoflurane 29 reports · 1.0% of its reports
Elevated amylase after Atipamezole 22 reports · 0.8% of its reports
Elevated amylase after Famotidine 42 reports · 1.6% of its reports

All reported side effects of Melarsomine in dogs · Medicines most reported with elevated amylase