Cyanosis after Melarsomine (Immiticide) in dogs

188 reports to the FDA describe cyanosis in dogs given Melarsomine. That is 0.8% of all reports for this medicine, compared with 0.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

188Reports
48%Marked serious
13%Recovered
30%Died or euthanised
2 daysTypical onset
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How soon it started

Same day
38 42%
1–2 days
9 9.9%
3–7 days
4 4.4%
1–4 weeks
16 18%
Over a month
24 26%

How the animals did

Recovered
23 12%
Recovered with lasting effects
1 0.5%
Still unwell when reported
26 14%
Died
52 28%
Euthanised
5 2.7%
Not known
81 43%

Problems reported at the same time

Age of the animals

Under 1 year
1
1–3 years
73
4–7 years
73
8–11 years
25
12+ years
5

About this medicine

Melarsomine treats adult heartworm infection (a series of injections given by a vet).

Products with this ingredient include Immiticide, Diroban. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Melarsomine cause cyanosis in dogs?
188 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 2 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Cyanosis with similar medicines

All reported side effects of Melarsomine in dogs · Medicines most reported with cyanosis