Neutropenia after Maropitant (Cerenia) in dogs

The FDA has received 188 reports of neutropenia in dogs after Maropitant. That is 1.6% of all reports for this medicine, compared with 0.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

188Reports

80%Marked serious

9.0%Recovered

43%Died or euthanised

4 daysTypical onset

How soon it started

Same day

36 24%

1–2 days

30 20%

3–7 days

23 15%

1–4 weeks

23 15%

Over a month

37 25%

How the animals did

Recovered

17 9.0%

Still unwell when reported

67 36%

Died

34 18%

Euthanised

46 24%

Not known

24 13%

Problems reported at the same time

114 61%

107 57%

96 51%

95 51%

79 42%

78 41%

75 40%

74 39%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Maropitant prevents vomiting and motion sickness.

Products with this ingredient include Cerenia. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Maropitant cause neutropenia in dogs?: 188 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 4 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Neutropenia with similar medicines

Neutropenia after Capromorelin (Entyce) 26 reports · 1.7% of its reports

All reported side effects of Maropitant in dogs · Medicines most reported with neutropenia