Leucopenia after Maropitant (Cerenia) in dogs

253 reports to the FDA describe leucopenia in dogs given Maropitant. That is 2.1% of all reports for this medicine, compared with 0.3% across reports for all dog medicines, so it is reported unusually often with this medicine.

253Reports

68%Marked serious

6.7%Recovered

40%Died or euthanised

3 daysTypical onset

How soon it started

Same day

51 26%

1–2 days

37 19%

3–7 days

32 16%

1–4 weeks

32 16%

Over a month

47 24%

How the animals did

Recovered

17 6.7%

Still unwell when reported

99 39%

Died

56 22%

Euthanised

45 18%

Not known

36 14%

Problems reported at the same time

138 55%

127 50%

121 48%

116 46%

101 40%

101 40%

94 37%

77 30%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Maropitant prevents vomiting and motion sickness.

Products with this ingredient include Cerenia. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Maropitant cause leucopenia in dogs?: 253 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 3 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

All reported side effects of Maropitant in dogs · Medicines most reported with leucopenia