Lymphadenopathy after Lokivetmab (Cytopoint) in dogs

32 reports to the FDA describe lymphadenopathy in dogs given Lokivetmab. That is 0.5% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

32Reports
69%Marked serious
0.0%Recovered
13%Died or euthanised
21 daysTypical onset
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How soon it started

Same day
3 13%
1–2 days
2 8.7%
3–7 days
3 13%
1–4 weeks
4 17%
Over a month
11 48%

How the animals did

Still unwell when reported
28 88%
Died
2 6.3%
Euthanised
2 6.3%

Problems reported at the same time

Age of the animals

Under 1 year
4
1–3 years
2
4–7 years
6
8–11 years
14
12+ years
4

About this medicine

Lokivetmab controls allergic itch for 4–8 weeks per injection.

Products with this ingredient include Cytopoint. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Lokivetmab cause lymphadenopathy in dogs?
32 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 21 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Lymphadenopathy with similar medicines

All reported side effects of Lokivetmab in dogs · Medicines most reported with lymphadenopathy