Hypoproteinaemia after Lokivetmab (Cytopoint) in dogs

The FDA has received 28 reports of hypoproteinaemia in dogs after Lokivetmab. That is 0.4% of all reports for this medicine, compared with 0.3% across reports for all dog medicines.

28Reports

64%Marked serious

11%Recovered

18%Died or euthanised

8 daysTypical onset

How soon it started

Same day

7 30%

1–2 days

3 13%

3–7 days

1 4.3%

1–4 weeks

4 17%

Over a month

8 35%

How the animals did

Recovered

3 11%

Still unwell when reported

20 71%

Died

1 3.6%

Euthanised

4 14%

Problems reported at the same time

17 61%

14 50%

14 50%

13 46%

13 46%

Reduced globulins

11 39%

Liver problems

10 36%

Diarrhea

9 32%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Lokivetmab controls allergic itch for 4–8 weeks per injection.

Products with this ingredient include Cytopoint. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Lokivetmab cause hypoproteinaemia in dogs?: 28 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 8 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Hypoproteinaemia with similar medicines

Hypoproteinaemia after Bedinvetmab (Librela) 39 reports · 0.2% of its reports

All reported side effects of Lokivetmab in dogs · Medicines most reported with hypoproteinaemia