Drooling after Lokivetmab (Cytopoint) in dogs

The FDA has received 123 reports of drooling in dogs after Lokivetmab. That is 1.9% of all reports for this medicine, compared with 1.4% across reports for all dog medicines.

123Reports

63%Marked serious

21%Recovered

14%Died or euthanised

3 daysTypical onset

How soon it started

Same day

30 30%

1–2 days

17 17%

3–7 days

17 17%

1–4 weeks

16 16%

Over a month

21 21%

How the animals did

Recovered

26 21%

Still unwell when reported

69 56%

Died

7 5.7%

Euthanised

10 8.1%

Not known

11 8.9%

Problems reported at the same time

57 46%

56 46%

46 37%

23 19%

22 18%

20 16%

20 16%

18 15%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Lokivetmab controls allergic itch for 4–8 weeks per injection.

Products with this ingredient include Cytopoint. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Lokivetmab cause drooling in dogs?: 123 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 3 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Drooling with similar medicines

Drooling after Bedinvetmab (Librela) 349 reports · 1.8% of its reports

All reported side effects of Lokivetmab in dogs · Medicines most reported with drooling