Reluctant to move after Ivermectin (Heartgard) in dogs

56 reports to the FDA describe reluctant to move in dogs given Ivermectin. That is 0.5% of all reports for this medicine, compared with 0.5% across reports for all dog medicines.

56Reports

34%Marked serious

25%Recovered

14%Died or euthanised

31 daysTypical onset

How soon it started

Same day

5 16%

1–2 days

2 6.3%

3–7 days

5 16%

1–4 weeks

4 13%

Over a month

16 50%

How the animals did

Recovered

12 21%

Recovered with lasting effects

2 3.6%

Still unwell when reported

10 18%

Died

4 7.1%

Euthanised

4 7.1%

Not known

24 43%

Problems reported at the same time

22 39%

16 29%

15 27%

14 25%

12 21%

11 20%

Eye or vision problems

10 18%

Liver problems

9 16%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Ivermectin prevents heartworm disease (monthly).

Products with this ingredient include Heartgard. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Some herding breeds (for example Collies) carry the MDR1 gene variant and can be more sensitive to this drug class at high doses.

Questions owners ask

Can Ivermectin cause reluctant to move in dogs?: 56 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 31 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Reluctant to move with similar medicines

Reluctant to move after Ivermectin + Pyrantel (Heartgard Plus) 256 reports · 0.2% of its reports
Reluctant to move after Milbemycin Oxime + Spinosad (Trifexis) 394 reports · 0.3% of its reports
Reluctant to move after Moxidectin (ProHeart 6) 290 reports · 0.6% of its reports
Reluctant to move after Milbemycin Oxime + Praziquantel (Interceptor Plus) 84 reports · 0.3% of its reports
Reluctant to move after Milbemycin Oxime (Interceptor) 64 reports · 0.2% of its reports
Reluctant to move after Selamectin (Revolution) 86 reports · 0.3% of its reports
Reluctant to move after Ivermectin + Praziquantel + Pyrantel (Iverhart Max) 26 reports · 0.3% of its reports

All reported side effects of Ivermectin in dogs · Medicines most reported with reluctant to move