Thrombocytosis after Insulin in dogs

54 reports to the FDA describe thrombocytosis in dogs given Insulin. That is 0.7% of all reports for this medicine, compared with 0.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

54Reports

89%Marked serious

22%Recovered

26%Died or euthanised

35 daysTypical onset

How soon it started

Same day

4 14%

1–2 days

0 0.0%

3–7 days

4 14%

1–4 weeks

5 18%

Over a month

15 54%

How the animals did

Recovered with lasting effects

12 22%

Still unwell when reported

15 28%

Died

4 7.4%

Euthanised

10 19%

Not known

13 24%

Problems reported at the same time

Liver problems

31 57%

Didn't work as expected

30 56%

24 44%

20 37%

18 33%

18 33%

Elevated cholesterol (total)

17 31%

Loss of appetite

16 30%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Insulin treats diabetes.

Questions owners ask

Can Insulin cause thrombocytosis in dogs?: 54 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 35 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Thrombocytosis with similar medicines

Thrombocytosis after Trilostane (Vetoryl) 453 reports · 3.8% of its reports
Thrombocytosis after Levothyroxine 33 reports · 1.1% of its reports

All reported side effects of Insulin in dogs · Medicines most reported with thrombocytosis