Leucocytosis after Insulin in dogs

The FDA has received 78 reports of leucocytosis in dogs after Insulin. That is 1.1% of all reports for this medicine, compared with 1.0% across reports for all dog medicines.

78Reports

88%Marked serious

13%Recovered

35%Died or euthanised

21 daysTypical onset

How soon it started

Same day

7 15%

1–2 days

5 11%

3–7 days

5 11%

1–4 weeks

9 20%

Over a month

20 43%

How the animals did

Recovered

4 5.1%

Recovered with lasting effects

6 7.7%

Still unwell when reported

27 35%

Died

14 18%

Euthanised

13 17%

Not known

14 18%

Problems reported at the same time

41 53%

37 47%

36 46%

34 44%

Didn't work as expected

33 42%

Neutrophilia

33 42%

Death

27 35%

Kidney problems

25 32%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Insulin treats diabetes.

Questions owners ask

Can Insulin cause leucocytosis in dogs?: 78 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 21 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Leucocytosis with similar medicines

Leucocytosis after Trilostane (Vetoryl) 190 reports · 1.6% of its reports
Leucocytosis after Phenylpropanolamine (Proin) 47 reports · 1.1% of its reports
Leucocytosis after Levothyroxine 47 reports · 1.6% of its reports

All reported side effects of Insulin in dogs · Medicines most reported with leucocytosis