Elevated gamma-glutamyl transferase (ggt) after Insulin in dogs

54 reports to the FDA describe elevated gamma-glutamyl transferase (ggt) in dogs given Insulin. That is 0.7% of all reports for this medicine, compared with 0.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

54Reports
85%Marked serious
11%Recovered
22%Died or euthanised
25 daysTypical onset
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How soon it started

Same day
7 27%
1–2 days
3 12%
3–7 days
3 12%
1–4 weeks
1 3.8%
Over a month
12 46%

How the animals did

Recovered
2 3.7%
Recovered with lasting effects
4 7.4%
Still unwell when reported
20 37%
Died
1 1.9%
Euthanised
11 20%
Not known
16 30%

Problems reported at the same time

Liver problems
49 91%
Didn't work as expected
23 43%
Elevated cholesterol (total)
22 41%
Loss of appetite
21 39%
Vomiting
19 35%
Lethargy
19 35%
Kidney problems
18 33%
Hyperglycaemia
16 30%

Age of the animals

Under 1 year
0
1–3 years
0
4–7 years
4
8–11 years
37
12+ years
13

About this medicine

Insulin treats diabetes.

Questions owners ask

Can Insulin cause elevated gamma-glutamyl transferase (ggt) in dogs?
54 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 25 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Elevated gamma-glutamyl transferase (ggt) with similar medicines

All reported side effects of Insulin in dogs · Medicines most reported with elevated gamma-glutamyl transferase (ggt)