Elevated amylase after Insulin in dogs

The FDA has received 45 reports of elevated amylase in dogs after Insulin. That is 0.6% of all reports for this medicine, compared with 0.3% across reports for all dog medicines, so it is reported unusually often with this medicine.

45Reports

84%Marked serious

22%Recovered

31%Died or euthanised

14 daysTypical onset

How soon it started

Same day

5 20%

1–2 days

3 12%

3–7 days

4 16%

1–4 weeks

5 20%

Over a month

8 32%

How the animals did

Recovered

6 13%

Recovered with lasting effects

4 8.9%

Still unwell when reported

11 24%

Died

7 16%

Euthanised

7 16%

Not known

10 22%

Problems reported at the same time

Elevated lipase

30 67%

Vomiting

22 49%

Didn't work as expected

21 47%

19 42%

19 42%

17 38%

16 36%

14 31%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Insulin treats diabetes.

Questions owners ask

Can Insulin cause elevated amylase in dogs?: 45 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 14 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Elevated amylase with similar medicines

Elevated amylase after Trilostane (Vetoryl) 135 reports · 1.1% of its reports

All reported side effects of Insulin in dogs · Medicines most reported with elevated amylase