Skin sore after Imidacloprid + Moxidectin (Advantage Multi) in dogs
The FDA has received 73 reports of skin sore in dogs after Imidacloprid + Moxidectin. That is 0.6% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.
73Reports
60%Marked serious
26%Recovered
1.4%Died or euthanised
10 daysTypical onset
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How soon it started
How the animals did
Problems reported at the same time
Age of the animals
About this medicine
Imidacloprid kills fleas (spot-on or collar). Moxidectin prevents heartworm disease (monthly topical, or a 6- or 12-month injection for dogs).
Products with this combination include Advantage Multi. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.
Questions owners ask
- Can Imidacloprid + Moxidectin cause skin sore in dogs?
- 73 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
- How soon after a dose was it reported?
- In half of the reports with dates, it started within 10 days of the first dose.
- What should I do?
- Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).
Skin sore with similar medicines
- Skin sore after Spinosad (Comfortis) 85 reports · 0.1% of its reports
- Skin sore after Lufenuron + Milbemycin Oxime (Sentinel) 27 reports · 0.1% of its reports
- Skin sore after Nitenpyram (Capstar) 47 reports · 0.4% of its reports
- Skin sore after Flumethrin + Imidacloprid (Seresto) 28 reports · 1.2% of its reports
All reported side effects of Imidacloprid + Moxidectin in dogs · Medicines most reported with skin sore