Polypnoea after Imidacloprid + Moxidectin (Advantage Multi) in dogs
The FDA has received 70 reports of polypnoea in dogs after Imidacloprid + Moxidectin. That is 0.5% of all reports for this medicine, compared with 0.5% across reports for all dog medicines.
70Reports
0.0%Marked serious
0.0%Recovered
2.9%Died or euthanised
–Typical onset
Sponsored
How the animals did
Problems reported at the same time
Age of the animals
About this medicine
Imidacloprid kills fleas (spot-on or collar). Moxidectin prevents heartworm disease (monthly topical, or a 6- or 12-month injection for dogs).
Products with this combination include Advantage Multi. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.
Questions owners ask
- Can Imidacloprid + Moxidectin cause polypnoea in dogs?
- 70 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
- What should I do?
- Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).
Polypnoea with similar medicines
- Polypnoea after Spinosad (Comfortis) 200 reports · 0.4% of its reports
- Polypnoea after Lufenuron + Milbemycin Oxime (Sentinel) 66 reports · 0.3% of its reports
- Polypnoea after Nitenpyram (Capstar) 60 reports · 0.6% of its reports
All reported side effects of Imidacloprid + Moxidectin in dogs · Medicines most reported with polypnoea