Low thyroxine (t4) after Ilunocitinib (Zenrelia) in dogs
The FDA has received 27 reports of low thyroxine (t4) in dogs after Ilunocitinib. That is 1.2% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.
27Reports
33%Marked serious
0.0%Recovered
22%Died or euthanised
93 daysTypical onset
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How soon it started
How the animals did
Problems reported at the same time
Age of the animals
About this medicine
Ilunocitinib controls itching from allergies (tablet, a JAK inhibitor).
Products with this ingredient include Zenrelia. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.
Questions owners ask
- Can Ilunocitinib cause low thyroxine (t4) in dogs?
- 27 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
- How soon after a dose was it reported?
- In half of the reports with dates, it started within 93 days of the first dose.
- What should I do?
- Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).
Low thyroxine (t4) with similar medicines
- Low thyroxine (t4) after Oclacitinib (Apoquel) 65 reports · 0.2% of its reports
All reported side effects of Ilunocitinib in dogs · Medicines most reported with low thyroxine (t4)