Breathing problems after Hydroxyzine in dogs

The FDA has received 51 reports of breathing problems in dogs after Hydroxyzine. That is 4.9% of all reports for this medicine, compared with 2.7% across reports for all dog medicines, so it is reported unusually often with this medicine.

51Reports

59%Marked serious

37%Recovered

12%Died or euthanised

44 daysTypical onset

How soon it started

Same day

3 7.7%

1–2 days

4 10%

3–7 days

4 10%

1–4 weeks

7 18%

Over a month

21 54%

How the animals did

Recovered

17 33%

Recovered with lasting effects

2 3.9%

Still unwell when reported

19 37%

Died

2 3.9%

Euthanised

4 7.8%

Not known

7 14%

Problems reported at the same time

18 35%

15 29%

14 27%

13 25%

11 22%

Restlessness or agitation

10 20%

Abnormal radiograph finding

9 18%

Diarrhea

8 16%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: medicine.

Questions owners ask

Can Hydroxyzine cause breathing problems in dogs?: 51 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 44 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Breathing problems with similar medicines

Breathing problems after Melarsomine (Immiticide) 1,801 reports · 7.9% of its reports
Breathing problems after Polysulfated Glycosaminoglycan 275 reports · 5.0% of its reports
Breathing problems after Diphenhydramine 574 reports · 12% of its reports
Breathing problems after Butorphanol 404 reports · 9.1% of its reports
Breathing problems after Cefpodoxime 198 reports · 4.9% of its reports
Breathing problems after Tramadol 375 reports · 10.0% of its reports
Breathing problems after Florfenicol + Mometasone + Terbinafine 163 reports · 4.6% of its reports
Breathing problems after Desoxycorticosterone Pivalate 135 reports · 4.0% of its reports
Breathing problems after Propofol 256 reports · 8.3% of its reports
Breathing problems after Dirlotapide 35 reports · 1.2% of its reports

All reported side effects of Hydroxyzine in dogs · Medicines most reported with breathing problems