Injection site reaction after Hydromorphone in dogs

128 reports to the FDA describe injection site reaction in dogs given Hydromorphone. That is 12% of all reports for this medicine, compared with 1.0% across reports for all dog medicines, so it is reported unusually often with this medicine.

128Reports

48%Marked serious

32%Recovered

5.5%Died or euthanised

2 daysTypical onset

How soon it started

Same day

37 32%

1–2 days

27 23%

3–7 days

21 18%

1–4 weeks

19 16%

Over a month

12 10%

How the animals did

Recovered

41 32%

Still unwell when reported

37 29%

Died

3 2.3%

Euthanised

4 3.1%

Not known

43 34%

Problems reported at the same time

Swelling

70 55%

Loss of appetite

25 20%

Pain

22 17%

Didn't work as expected

18 14%

Lameness

16 13%

Hair loss

11 8.6%

Application site reaction

11 8.6%

Lethargy

11 8.6%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: medicine.

Questions owners ask

Can Hydromorphone cause injection site reaction in dogs?: 128 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 2 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Injection site reaction with similar medicines

Injection site reaction after Melarsomine (Immiticide) 3,290 reports · 15% of its reports
Injection site reaction after Polysulfated Glycosaminoglycan 263 reports · 4.8% of its reports
Injection site reaction after Diphenhydramine 398 reports · 8.4% of its reports
Injection site reaction after Butorphanol 479 reports · 11% of its reports
Injection site reaction after Cefpodoxime 81 reports · 2.0% of its reports
Injection site reaction after Tramadol 123 reports · 3.3% of its reports
Injection site reaction after Desoxycorticosterone Pivalate 165 reports · 4.9% of its reports
Injection site reaction after Propofol 170 reports · 5.5% of its reports
Injection site reaction after Isoflurane 126 reports · 4.6% of its reports
Injection site reaction after Cephalexin 31 reports · 1.2% of its reports

All reported side effects of Hydromorphone in dogs · Medicines most reported with injection site reaction