Hyaluronic Acid side effects in dogs

91 reports sent to the FDA between 2013 and 2025 involve Hyaluronic Acid in dogs. The most reported problems were vomiting, ocular discharge, corneal ulcer. 64% were marked serious.

91Reports
64%Marked serious
19%Only medicine involved
33%Recovered
9.9%Died or euthanised
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About this medicine

Type: medicine.

Most reported side effects

Vomiting
18 20%
Ocular discharge
17 19%
Corneal ulcer
17 19%
Lethargy
14 15%
Diarrhea
13 14%
Eye pain
13 14%
Skin redness
13 14%
Squinting
12 13%
Eye or vision problems
11 12%
Loss of appetite
11 12%
Behaviour change
10 11%
Blepharospasm
9 9.9%
Eye disorder (for photophobia see 'neurological')
9 9.9%
Liver problems
8 8.8%
Keratoconjunctivitis sicca
8 8.8%

Share = percentage of this medicine's reports that mention the problem. One report can list several problems.

Reports that it didn't work

Some reports are about the medicine not working (for example a dog still getting fleas or heartworm), not about a side effect.

Didn't work as expected
13 14%

How soon problems started

Same day
19 30%
1–2 days
12 19%
3–7 days
8 13%
1–4 weeks
12 19%
Over a month
13 20%

Time from the first dose to the first sign, where both dates were reported (64 reports).

How the animals did

Recovered
30 33%
Still unwell when reported
10 11%
Died
5 5.5%
Euthanised
4 4.4%
Not known
42 46%

Breeds named most often

Popular breeds appear more often because there are more of them.

Other medicines for dogs