Frontline Plus side effects in dogs
60 reports sent to the FDA between 2011 and 2025 involve Frontline Plus in dogs. The most reported problems were lethargy, vomiting, loss of appetite. 38% were marked serious.
60Reports
38%Marked serious
0.0%Only medicine involved
37%Recovered
5.0%Died or euthanised
Sponsored
About this medicine
Type: medicine.
Most reported side effects
Share = percentage of this medicine's reports that mention the problem. One report can list several problems.
Reports that it didn't work
Some reports are about the medicine not working (for example a dog still getting fleas or heartworm), not about a side effect.
How soon problems started
Time from the first dose to the first sign, where both dates were reported (35 reports).
How the animals did
Breeds named most often
Popular breeds appear more often because there are more of them.
- Labrador Retriever 9 reports
- Dog (other) 6 reports
- Golden Retriever 4 reports
- Yorkshire Terrier 4 reports
- Cocker American Spaniel 2 reports
- Shetland Sheepdog 2 reports
- Bichon Frise 2 reports
- Lhasa Apso 2 reports
- West Highland White Terrier 1 reports
- German Pomeranian Spitz 1 reports
Other medicines for dogs
Melarsomine (Immiticide)22,672 reports · 41% seriousPolysulfated Glycosaminoglycan5,465 reports · 33% seriousDiphenhydramine4,724 reports · 48% seriousButorphanol4,441 reports · 55% seriousCefpodoxime4,055 reports · 36% seriousTramadol3,768 reports · 47% seriousFlorfenicol + Mometasone + Terbinafine3,542 reports · 60% seriousDesoxycorticosterone Pivalate3,337 reports · 38% serious