Weak pulse after Fluralaner (Bravecto) in dogs

The FDA has received 46 reports of weak pulse in dogs after Fluralaner. That is 0.1% of all reports for this medicine, compared with 0.1% across reports for all dog medicines.

46Reports

100%Marked serious

11%Recovered

61%Died or euthanised

1 daysTypical onset

How soon it started

Same day

15 45%

1–2 days

5 15%

3–7 days

3 9.1%

1–4 weeks

2 6.1%

Over a month

8 24%

How the animals did

Recovered

5 11%

Still unwell when reported

9 20%

Died

11 24%

Euthanised

17 37%

Not known

4 8.7%

Problems reported at the same time

29 63%

29 63%

26 57%

21 46%

20 43%

19 41%

18 39%

17 37%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Fluralaner kills fleas and ticks for up to 12 weeks (chewable or spot-on).

Products with this ingredient include Bravecto. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

In 2018 the FDA alerted owners and vets that isoxazoline products have been associated with neurologic reactions such as muscle tremors, wobbliness (ataxia) and seizures, including in animals with no history of them.

Questions owners ask

Can Fluralaner cause weak pulse in dogs?: 46 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 1 day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Weak pulse with similar medicines

Weak pulse after Afoxolaner (NexGard) 20 reports · 0.0% of its reports

All reported side effects of Fluralaner in dogs · Medicines most reported with weak pulse