Tachycardia after Fluralaner (Bravecto) in dogs

The FDA has received 170 reports of tachycardia in dogs after Fluralaner. That is 0.2% of all reports for this medicine, compared with 0.5% across reports for all dog medicines, so it is reported less often than average with this medicine.

170Reports
92%Marked serious
26%Recovered
30%Died or euthanised
1 daysTypical onset
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How soon it started

Same day
43 38%
1–2 days
24 21%
3–7 days
11 9.8%
1–4 weeks
11 9.8%
Over a month
23 21%

How the animals did

Recovered
36 21%
Recovered with lasting effects
8 4.7%
Still unwell when reported
60 35%
Died
23 14%
Euthanised
28 16%
Not known
15 8.8%

Problems reported at the same time

Age of the animals

Under 1 year
14
1–3 years
47
4–7 years
42
8–11 years
44
12+ years
22

About this medicine

Fluralaner kills fleas and ticks for up to 12 weeks (chewable or spot-on).

Products with this ingredient include Bravecto. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

In 2018 the FDA alerted owners and vets that isoxazoline products have been associated with neurologic reactions such as muscle tremors, wobbliness (ataxia) and seizures, including in animals with no history of them.

Questions owners ask

Can Fluralaner cause tachycardia in dogs?
170 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 1 day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Tachycardia with similar medicines

All reported side effects of Fluralaner in dogs · Medicines most reported with tachycardia