Neurological signs after Fluralaner (Bravecto) in dogs

153 reports to the FDA describe neurological signs in dogs given Fluralaner. That is 0.2% of all reports for this medicine, compared with 0.3% across reports for all dog medicines.

153Reports
83%Marked serious
28%Recovered
20%Died or euthanised
4 daysTypical onset
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How soon it started

Same day
16 22%
1–2 days
19 26%
3–7 days
7 9.5%
1–4 weeks
12 16%
Over a month
20 27%

How the animals did

Recovered
38 25%
Recovered with lasting effects
5 3.3%
Still unwell when reported
62 41%
Died
14 9.2%
Euthanised
17 11%
Not known
17 11%

Problems reported at the same time

Age of the animals

Under 1 year
13
1–3 years
35
4–7 years
42
8–11 years
27
12+ years
25

About this medicine

Fluralaner kills fleas and ticks for up to 12 weeks (chewable or spot-on).

Products with this ingredient include Bravecto. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

In 2018 the FDA alerted owners and vets that isoxazoline products have been associated with neurologic reactions such as muscle tremors, wobbliness (ataxia) and seizures, including in animals with no history of them.

Questions owners ask

Can Fluralaner cause neurological signs in dogs?
153 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 4 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Neurological signs with similar medicines

All reported side effects of Fluralaner in dogs · Medicines most reported with neurological signs