Lameness after Fluralaner (Bravecto) in dogs

362 reports to the FDA describe lameness in dogs given Fluralaner. That is 0.5% of all reports for this medicine, compared with 0.6% across reports for all dog medicines.

362Reports

82%Marked serious

20%Recovered

14%Died or euthanised

5 daysTypical onset

How soon it started

Same day

48 24%

1–2 days

41 21%

3–7 days

21 11%

1–4 weeks

29 15%

Over a month

57 29%

How the animals did

Recovered

58 16%

Recovered with lasting effects

13 3.6%

Still unwell when reported

189 52%

Died

11 3.0%

Euthanised

38 10%

Not known

53 15%

Problems reported at the same time

119 33%

95 26%

71 20%

64 18%

52 14%

49 14%

49 14%

43 12%

Age of the animals

Under 1 year

1–3 years

4–7 years

101

8–11 years

111

12+ years

About this medicine

Fluralaner kills fleas and ticks for up to 12 weeks (chewable or spot-on).

Products with this ingredient include Bravecto. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

In 2018 the FDA alerted owners and vets that isoxazoline products have been associated with neurologic reactions such as muscle tremors, wobbliness (ataxia) and seizures, including in animals with no history of them.

Questions owners ask

Can Fluralaner cause lameness in dogs?: 362 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 5 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Lameness with similar medicines

Lameness after Afoxolaner (NexGard) 337 reports · 0.6% of its reports
Lameness after Sarolaner (Simparica) 88 reports · 0.5% of its reports
Lameness after Lotilaner (Credelio) 149 reports · 1.5% of its reports
Lameness after Afoxolaner + Moxidectin + Pyrantel (NexGard PLUS) 43 reports · 0.5% of its reports
Lameness after Lotilaner + Moxidectin + Praziquantel + Pyrantel (Credelio Quattro) 36 reports · 1.2% of its reports

All reported side effects of Fluralaner in dogs · Medicines most reported with lameness