Inappropriate defecation after Fluralaner (Bravecto) in dogs

183 reports to the FDA describe inappropriate defecation in dogs given Fluralaner. That is 0.3% of all reports for this medicine, compared with 0.2% across reports for all dog medicines.

183Reports
78%Marked serious
37%Recovered
16%Died or euthanised
1 daysTypical onset
SponsoredWorried about your pet? Ask a veterinarian online, 24/7

How soon it started

Same day
31 24%
1–2 days
45 35%
3–7 days
16 13%
1–4 weeks
11 8.7%
Over a month
24 19%

How the animals did

Recovered
65 36%
Recovered with lasting effects
3 1.6%
Still unwell when reported
67 37%
Died
13 7.1%
Euthanised
16 8.7%
Not known
19 10%

Problems reported at the same time

Age of the animals

Under 1 year
16
1–3 years
39
4–7 years
40
8–11 years
47
12+ years
37

About this medicine

Fluralaner kills fleas and ticks for up to 12 weeks (chewable or spot-on).

Products with this ingredient include Bravecto. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

In 2018 the FDA alerted owners and vets that isoxazoline products have been associated with neurologic reactions such as muscle tremors, wobbliness (ataxia) and seizures, including in animals with no history of them.

Questions owners ask

Can Fluralaner cause inappropriate defecation in dogs?
183 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 1 day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Inappropriate defecation with similar medicines

All reported side effects of Fluralaner in dogs · Medicines most reported with inappropriate defecation